Current Pediatric Research

Introduction: Nephrolithiasis, as a major health issue, have significant contribution to wide surgical procedures and loss of kidney. In addition, serum electrolytes level specially Zinc level, affect renal function. This paper is intended to get to the relationship between serum Zinc level and development of nephrolithiasis in children. Material and methods: In this as a case-control study, with a random sampling method, 2-18 years old children who reffered to Amir-Kabir Hospital, we selected 208 children with nephrolithiasis as case and 208 children without nephrolithiatic as control groups. Ultrasonography was performed for both groups. Urine and blood were analyzed and based on this serum and urinary metabolic problems were evaluated. Also demographic information was being taken from patients. Data were analyzed by independent T-test and regression logistic test in the SPSS21 statistical software. Results: Although the serum Zinc level in case group were higher than control group, but this difference is not statistically significant (p=0). Conclusion: Relationship between nephrolithiasis and serum Zinc level has not been approved but with urinary Zinc level has been approved.

Author(s): Parsa Yousefichaijan, Masoud Rezagholizamenjany, Fatemeh Dorreh, Mohamad Rafiei, Hassan Taherahmadi, Ali Arjmand, Simin Kianmanesh, Mojgan Zarini

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